Enwere m ike ịgwọ ịda mbà n'obi m site na iji curcumin kama ọgwụ?
Ị nwere ike iji curcumin maka ịda mbà n'obi. Enweela ọtụtụ ule a na-achịkwa na-egosi ịdị irè kpọmkwem maka ịda mbà n'obi. Curcumin na-elekwasị anya neuroinflammation nke nwere ọrụ siri ike na-akpata mgbaàmà ịda mbà n'obi. Enwere ụdị curcumin dị ndụ nke ndị nwere nkụda mmụọ nwere ike iwere maka nsonaazụ ka mma. Enwere ike iji ya ma ọ bụ na-enweghị ọgwụ.
Tebulu ọdịnaya
- Okwu Mmalite
- Kedu ka curcumin si arụ ọrụ iji belata neuroinflammation na ịda mbà n'obi?
- Kedu ihe ọzọ curcumin nwere ike ime iji nyere aka ịda mbà n'obi?
- Kedu ihe kacha mma curcumin ị ga-ewere?
- Kedu ka m ga-esi eji curcumin belata neuroinflammation ma nyere m aka ịda mbà n'obi?
- Curcumin ọ ga-agwọ ịda mbà n'obi m?
- mmechi
- References
Okwu Mmalite
Bọọgụ blọgụ a bụ otu n'ime usoro banyere antioxidants nke nwere ike inye aka maka ịda mbà n'obi ma gụnyere Curcumin, Quercetin, na OPC.
Agaghị m agwụ gị ozi na curcumin sitere na mgbọrọgwụ turmeric. N'ihi na ejiri m n'aka na ị maworị nke ahụ ma ọ bụ nwee ike ịhụ 100 blọọgụ posts na-ekwu maka nke ahụ.
Kama, m ga-akụziri gị na curcumin nwere ọtụtụ usoro nwere ike inye aka belata ịda mbà n'obi. Usoro abụọ a na-eme ihe nke nwere ike bụrụ ihe kachasị mkpa na ọrịa uche dị ka ịda mbà n'obi bụ ike ya dị ka antioxidant na mmetụta neuroprotective ya.
Ọ bụrụ na ị na-enyocha akwụkwọ ahụ n'onwe gị, ị nwere ike ịkọwa na ọ bụghị ọtụtụ ọmụmụ na-egosi curcumin dị ka ọgwụgwọ dị irè maka ịda mbà n'obi. Isi ihe kpatara nke a bụ na ọtụtụ nyocha na-eleba anya n'ịrụ ọrụ ọgụgụ isi. Ya mere, a na-ewepụ ndị nwere ịda mbà n'obi na ọmụmụ ihe ndị ahụ n'ihi na nsogbu uche nke bụ akụkụ nke ịda mbà n'obi ga-abụ mgbanwe na-agbagwoju anya na ọmụmụ ihe na-anwa ịchụpụ mmetụta curcumin na dementias.
Nke ahụ apụtaghị na ọ dịghị ule ụlọ ọgwụ maka iji curcumin na ịda mbà n'obi. E nwere ọtụtụ, ma enweela ụfọdụ ndị na-eji ya na-ejighị ọgwụ eme ihe.
N'ime ule niile, ndị a na-amụ na-egosi ọganihu dị ịrịba ama na mgbaàmà ndị metụtara ịda mbà n'obi, nke a na-enyocha site na iji akpịrịkpa dị mkpa.
Rathore, S., Mukim, M., Sharma, P., Devi, S., Nagar, JC, & Khalid, M. (2020). Curcumin: Nlebanya maka uru ahụike. https://www.ijrrjournal.com/IJRR_Vol.7_Issue.1_Jan2020/Abstract_IJRR0039.html
N'etiti RCT ndị dị ugbu a na nchọpụta banyere mmetụta nke curcumin na mbufụt, e nwere ihe ọ bụla mere ị ga-eji tụlee curcumin dị ka ọgwụgwọ. Anyị achọpụtalarị ụfọdụ n'ime ọrịa ịda mbà n'obi nke ịda mbà n'obi na blọgụ ndị gara aga, ya mere, anyị maara na ịchọta mbufụt bụ usoro ọgwụgwọ dị mma maka ịgwọ ịda mbà n'obi na-enweghị ọgwụ (ma ọ bụ ya na-ahọrọ ya).
Kedu ka curcumin si arụ ọrụ iji belata neuroinflammation na ịda mbà n'obi?
Ndị mmadụ na-enwe nkụda mmụọ nwere ọtụtụ mbufụt nke ụbụrụ. Ya mere, ihe ọ bụla nwere ike ibelata mmepụta nke free radicals nke mmebi oxidative kpatara ga-aba uru. Njirimara antioxidant nke curcumin na-ebelata nrụgide oxidative na ụbụrụ, na-ebelata ịka nká neurodegenerative.
Mana abụ m onye na-eto eto, ị nwere ike ịsị. Echere m na blọgụ a bụ maka ịda mbà n'obi. Ọ bụghị ụdị dementia, dị ka ọrịa Alzheimer.
Abịara m ebe a ịgwa gị na afọ gị adịghị mkpa. Okwu neurodegenerative ịka nká ka na-emetụta.
Ọkwa mgbakasị ahụ nke oxidative na-achịkwaghị achịkwa, dị ka ihe ị nwere ike na-enwe na ịda mbà n'obi gị, ga-eme ka ụbụrụ gị dị ngwa ngwa karịa ka ọ chọrọ ịka nká. Ị nwere ike ịbụ 24 afọ, ma ọ bụrụ na ị nwere ịda mbà n'obi na neuroinflammation nke na-aga na nke ahụ, ị na-enweta ịka nká nke neurodegenerative. Curcumin nwere ike belata nke ahụ site n'ịlụso ndị radicals free ọgụ na ibelata nrụgide oxidative. Mmetụta neuroprotective nke curcumin na-enyere aka na ụbụrụ dara mbà n'obi na-ata ahụhụ site na mbufụt.
E wezụga ịbụ antioxidant, curcumin na-ebelata ọrụ microglial. Microglia bụ mkpụrụ ndụ na-arụ ọrụ mgbe ha hụrụ mwakpo (dịka ọmụmaatụ, ọbara shuga dị elu, ihe nfụkasị ahụ, nsị gburugburu ebe obibi, nnukwu nrụgide, wdg) na-eme na ụbụrụ. Ha na-emepụta nzaghachi mgbochi ọrịa n'ụbụrụ nke na-ahapụ cytokines mkpasu iwe na mbọ iji chebe ụbụrụ site na ụdị mwakpo ọ bụla nwere ike ime. Mana n'ịhapụ cytokines, ọ na-abawanye mbufụt.
Ihe nrịbama mkpali akọwapụtara nke anyị na-ahụ belata na Curcumin bụ IL-17, TNF-a, IL-6, TGF-β, na MCP-1.
Ị ga-enwerịrị micronutrients zuru oke yana usoro antioxidant endogenous dị mma iji rụkwaa mmebi ahụ mgbe microglial arụ ọrụ gị. Ma ọ bụrụ na ị dara mbà n'obi, ọ ga-abụ na ihe abụọ ahụ agwụla gị. Ya mere, ihe ọ bụla nke na-eme ka ahụ dị jụụ ma ọ bụ na-edozi ọrụ usoro ahụ ji alụso ọrịa ọgụ nke cell microglial nwere ike inye aka n'ibelata mbufụt na ụbụrụ.
Kedu ihe ọzọ curcumin nwere ike ime iji nyere aka ịda mbà n'obi?
Ewezuga ibelata neuroinflammation na nrụgide oxidative na ikike antioxidant ya dị egwu, curcumin nwere ike ime ọtụtụ usoro antidepressant ndị ọzọ nwere ike inyere gị aka ịgwọ ịda mba gị.
Mgbanwe nke mmepụta nke ọtụtụ neurotransmitter precursors nke na-eduga n'ịbawanye mmepụta nke serotonin na dopamine na cortex n'ihu. Ndị a bụ neurotransmitters anyị na-ahụkarị ụkọ nke ịda mbà n'obi.
Nkwalite nke ụbụrụ neurotrophic nke ụbụrụ na-enweta (BDNF) nke na-enyere ụbụrụ aka ịgwọ, wughachi ma mee ncheta ọhụrụ. Nke a dị mkpa n'ihi na mkpụrụ ndụ ụbụrụ kwesịrị ịgbake site na mmebi cellular n'ihi nrụgide oxidative na mbufụt. Onye ọ bụla dara mbà n'obi ga-agwa gị na ebe nchekwa adịghị adịte aka bụ n'ezie nsogbu.
Nkwalite ụzọ AMP cyclic (AC-cAMP), nke na-emepụta adenosine. Ma kedu ihe? Adenosine na-enyere aka ịchịkwa mbufụt. Ọ na-ekerekwa òkè na mmepụta nke GABA. GABA bụ neurotransmitter nke na-enyere gị aka inwe ahụ iru ala ma ghara ịkagbu ya, ọ na-emekarịkwa ya nke ọma na ụbụrụ dara mbà n'obi na-ata ahụhụ site na neuroinflammation.
Curcumin bụ onye na-emegide CB1 nnabata. A na-eji ọgwụ ndị na-anabata CB1 antagonist ugbu a na-agwọ ọrịa uche na ọrịa neurodegenerative. Ha na-emezigharị glutamate na ntọhapụ GABA, abụọ neurotransmitters na-emegide nke a na-ahụ ka ha na-adakọghị n'ọtụtụ ọrịa uche, gụnyere ịda mbà n'obi.
Ọ na-arụkwa ọrụ dị ka onye na-egbochi monoamine oxidase, enzyme nke na-akụda neurotransmitters. Ya mere curcumin ọ bụghị naanị na-abawanye mmepụta nke neurotransmitter, dị ka a tụlere n'elu, kamakwa na-enyere ndị neurotransmitters aka ịnọpụ na mgbawa synapti ogologo oge. Eleghị anya ị nụla maka ndị na-egbochi monoamine oxidase dị ka ọgwụ maka ịda mbà n'obi. Otu usoro. Enweghị ndenye ọgwụ ma ọ bụ mmetụta ọ bụla.
Kedu ihe kacha mma curcumin ị ga-ewere?
Curcumin adịghị adị nke ukwuu. Ngwakọta na ose ojii nwere ike ịbawanye bioavailability ya site na 2000%. Ịgbakwunye abụba ma ọ bụ mmanụ dị mma nwekwara ike ịbawanye bioavailability.
Ihe m na-aga imeju maka neuroinflammation bụ Curcumisorb Mind. A na-eme ihe niile nke antioxidant dị na mgbakwunye a maka nkwalite bioavailability. Ọ nwere ngwakọta nke antioxidants nke yiri ka ọ na-eme ka ọ dịkwuo mma.
Curcumisorb Mind - Encapsulations dị ọcha (ọ bụghị njikọ njikọ)
Nhọrọ ọzọ bụ ịnweta naanị turmeric ma ọ bụ mgbakwunye curcumin (nke nwere olile anya organic) mgbe niile ma jikọta ya na mgbakwunye piperine. Ihe mgbakwunye piperine bụ ihe na-arụ ọrụ na ose ojii nke na-abawanye nnabata nke curcumin site na 2000%.
Kedu ka m ga-esi eji curcumin belata neuroinflammation ma nyere m aka ịda mbà n'obi?
Maka Curcumasorb Mind kpọmkwem, dose ahụ bụ 1x kwa ụbọchị, ọ gwụla ma ị na-enwe mmetụta dị ịrịba ama ọdịda, mgbe ahụ, a na-eji 2x kwa ụbọchị. Ị nwere ike ikpebi usoro onunu ogwu gị nke ọma site na iji ozi a. Ọ bụrụ na ị nwere ọtụtụ mgbaama mgbaama nke bụ akụkụ nke ịda mbà n'obi gị, ị nwere ike ime nke ọma na 2x kwa ụbọchị maka mgbakwunye a kpọmkwem.
Ma ọ bụrụ na ị were obere curcumin bioavailable, ị ga-ewere 90 mg 2x kwa ụbọchị yana mgbakwunye piperine nke 5mg.
Curcumin ọ ga-agwọ ịda mbà n'obi m?
Ị nwere ike ịhụ nsonaazụ nke curcumin supplementation n'ime ihe dịka izu iri na abụọ, ma ọ bụ ọ nwere ike were ọnwa 12. Na-eche na ihe ndị ọzọ ị na-eme na ndụ gị nke na-ebute mbufụt abụghị nke ukwuu maka mgbakwunye gị ka ọ ghara igbochi ya.
Ụra na-adịghị mma, nsị gburugburu ebe obibi, nri ndị a na-edozi nke ọma nke jupụtara na shuga, na ihe ndị ọzọ na-akpasu iwe ma ọ bụ ihe omume bụ isi ihe na-akpata ịda mbà n'obi gị.
Mgbakwụnye dị ka curcumin agaghị agba gị ume ka emee nyocha ọrụ iji chọpụta ebe ụfọdụ n'ime mbufụt ahụ nwere ike isi na ya pụta. Curcumin agaghị agba gị ume ka ị na-eri nri bara ụba na-edozi ahụ, pụọ na anyanwụ, gaa ije ma ọ bụ chọta mmekọrịta na-adịghị mma. Ọ gaghị agwa gị ka ị na-eme yoga ma ọ bụ mee ọtụtụ ihe ndị ọzọ na-ebi ndụ ga-akwụsị isi iyi nke mbufụt gị ma ọ bụ, ma ọ dịkarịa ala, belata ya.
Ịgbanwe nri gị na ụzọ ndụ gị ga-abụ ihe enyemaka dị ike karị. Ana m akwado nke ukwuu nri ketogenic maka ịda mbà n'obi ụlọ ọgwụ.
Mana n'ihe gbasara ịgbalị ibelata mgbaàmà nke ịda mbà n'obi ị na-enwe ugbu a, curcumin nwere ike inye aka. Iji curcumin ma ọ bụ ngwakọta nke antioxidants gụnyere ya nwere ike inye aka belata neuroinflammation gị nke na ị nwere ike iche echiche maka ime mgbanwe ka ukwuu na mma.
mmechi
Dị ka mgbe niile, blọgụ a bụ ozi na ọ bụghị ndụmọdụ ahụike.
Ọ bụrụ na ị nwere data mkpụrụ ndụ ihe nketa 23andme, ị nwere ike ịga na saịtị a dị ịtụnanya akpọrọ Genetic Life Hacks (Mgbakwunye) wee mụta ka mkpụrụ ndụ ihe nketa gị si enye gị ohere igosipụta usoro dị n'okpuru na curcumin. Nke a bụ nnukwu saịtị iji nyochaa ma ọ bụrụ na ị nwere data gị. Njikọ a bụ kpọmkwem gbasara mbufụt!
Ọ bụrụ na ịnweghị data gị ma chọọ ịmụta banyere nutrigenomics yana otu ị ga-esi megharịa nhọrọ mgbakwunye gị maka ebumnuche ahụike gị, ị nwere ike ịme nnwale gị ebe ahụ, site na njikọ njikọ a ma ọ bụrụ na-amasị gị! 23andMe. Cheta, enwere ike ịkwụ ụgwọ otu akụkụ nke 23andMe gị na HSA ma ọ bụ FSA ma ọ bụrụ na ị nwere uru ahụ.
Ọ bụrụ na isiokwu ahụ dị n’elu ahụ́ na-enyere gị aka, ị ga-achọ ịgụ ihe atọ ndị a na-amụba n’ihe ndị ị mụtara ugbu a! Ị nwere ike chọọ ịmụta ebe neuroinflammation niile si na mbụ. Ma ị nwere ike chọọ ịmụtakwu ụzọ ị ga-esi mee ka ahụ dịkwuo gị mma.
Ọ bụrụ na ịchọrọ ịmatakwu banyere usoro ndị na-akpata ịda mbà n'obi n'ụzọ zuru ezu, ana m akwado nke ọma posts ndị a na isiokwu a.
Ọ bụrụ na ị nwere onye na-edepụta ọgwụ ugbu a nke amaghị ihe kpatara na ị na-ebulite nke ọ bụla n'ime ọgwụgwọ okike ndị a, ị nwere ike ịchọta onye na-edepụta ọgwụ na-arụ ọrụ isi mgbaka ma dị njikere ikwu maka nhọrọ dị iche iche, karịsịa ma ọ bụrụ na ị na-aṅụ ọgwụ maka gị. ịda mbà n'obi.
Abụ m onye ndụmọdụ ahụike uche nke na-eme ụkpụrụ isi mgbaka na-arụ ọrụ na nri nri. Azụlitela m mmemme dị n'ịntanetị dị ka onye nkuzi na onye nchịkwa ahụike na-arụ ọrụ ka m nwee ike inyere ọtụtụ ndị mmadụ aka ịmụta ụzọ niile ha nwere ike isi nwee ahụ iru ala. A na-akpọ ya mmemme mgbake ụbụrụ ụbụrụ.
Dị ka ihe ị na-agụ na blọgụ? Chọrọ ịmụta maka webinars na-abịa, nkuzi na ọbụna na-enye nkwado na iso m na-arụkọ ọrụ maka ebumnuche ọdịmma gị? Debanye aha!
References
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